LYN-1604 Modified

LYN-1604 ModifiedLYN 1604 is a potential ULK1 agonist with IC50 of 1. 66 ? M against MDA MB 231 cells and it binds to wild type ULK1 with a binding affinity in the nanomole range (Kd=291. 4 nM). The ULK1 (Y89A) mutant protein caused a sharp decrease in binding affinity with lower response and Kd than wild type ULK1, ULK1 (K50A) and ULK1 (L53A) mutants.

is a pure heart rate lowering agent

PF-00562271 is the benzenesulfonate salt of PF-562271

Idarubicin HCl is a hydrochloride salt form of Idarubicin which is an anthracycline antibiotic and a DNA topoisomerase II (topo II) inhibitor for MCF-7 cells with IC50 of 3

and antiproliferative activities

Coptisine is an isoquinoline alkaloid isolated from Coptidis Rhizoma with anti-diabetic

For replacement condensers

-secretase inhibitor

Nitisinone is a synthetic reversible inhibitor of 4-hydroxyphenylpyruvate dioxygenase used in the treatment of hereditary tyrosinemia type 1

200mL is equal to 100% in 1% divisions

it is originally developed for dermatologic applications

H-Cys(Trt)-OH is a specific inhibitor of Eg5 that inhibits Eg5-driven microtubule sliding velocity in a reversible fashion with an IC50 of 500 nM

4'-Dimethoxybenzil is a biochemical that has been reported to have mesomorphic properties of a substituted bis(dithiolene)nickel complex derived from 4